Does change in heart rate and blood pressure during adenosine stress perfusion cardiovascular magnetic resonance (A-CMRP) imaging predict perfusion defects?

نویسندگان

  • Krishnaraj S Rathod
  • Ceri Davies
  • Steffen E Petersen
  • Mark Westwood
  • Neha Sekhri
چکیده

Background Haemodynamic response to adenosine infusion during CMR stress perfusion continues to be used as surrogate to determine adequacy of hyperaemia in clinical setting. Our aim was to determine the proportion of patients who achieve pre-specified adequate response to adenosine (increase in heart rate (HR) by ≥ 10 beats or a drop in systolic blood pressure (SBP) by 10mm Hg from baseline reading) and if this varies in patients identified with and without perfusion defect in a clinical setting.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Feasibility and safety of high-dose adenosine perfusion cardiovascular magnetic resonance imaging

Introduction Adenosine is the most widely used vasodilator stress agent for Cardiovascular Magnetic Resonance (CMR) perfusion studies. With the standard dose of 140 mcg/ kg/min some patients fail to demonstrate characteristic hemodynamic changes: a significant increase in heart rate (HR) and mild decrease in systolic blood pressure (SBP). Whether an increase in the rate of adenosine infusion wo...

متن کامل

Cardiac magnetic resonance perfusion imaging using a single intravenous line

Background CMR perfusion (CMRP) imaging using adenosine is increasingly used for the assessment of patients with known or suspected coronary artery disease. The scanning protocol requires administration of intravenous adenosine to achieve maximum hyperaemia followed by acquisition of CMR images during first pass perfusion of gadolinium. Traditionally this involves placing two intravenous lines,...

متن کامل

Splenic T1-mapping: a novel quantitative method for assessing adenosine stress adequacy for cardiovascular magnetic resonance

BACKGROUND Perfusion cardiovascular magnetic resonance (CMR) performed with inadequate adenosine stress leads to false-negative results and suboptimal clinical management. The recently proposed marker of adequate stress, the "splenic switch-off" sign, detects splenic blood flow attenuation during stress perfusion (spleen appears dark), but can only be assessed after gadolinium first-pass, when ...

متن کامل

Relation Between Stress - Induced Myocardial Perfusion Defects on Cardiovascular Magnetic Resonance and Coronary Microvascular Dysfunction in Patients With Cardiac Syndrome

reversible myocardial perfusion defects during stress myocardial scintigraphy (2,3) and, even more, by the evidence of an impaired response to vasodilator stimuli of coronary blood flow and/or resistance, assessed with several different methods (4-10). In particular, a blunted increase in subendocardial flow in response to intravenous administration of adenosine (11) was shown by cardiovascular...

متن کامل

Effects of hyperaemia on left ventricular longitudinal strain in patients with suspected coronary artery disease

AIMS Myocardial perfusion imaging during hyperaemic stress is commonly used to detect coronary artery disease. The aim of this study was to investigate the relationship between left ventricular global longitudinal strain (GLS), strain rate (GLSR), myocardial early (E') and late diastolic velocities (A') with adenosine stress first-pass perfusion cardiovascular magnetic resonance (CMR) imaging. ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره 14  شماره 

صفحات  -

تاریخ انتشار 2012